NMNH (Reduced Nicotinamide Mononucleotide) is the reduced form of NMN and a next-generation NAD+ precursor scientifically proven to be significantly more potent than NMN. Veritas Patented NMNH Pellets utilize our proprietary microencapsulation technology to protect this sensitive compound, delivering 36-month stability and 24-hour sustained release for maximum therapeutic efficacy.
NMNH (Reduced Nicotinamide Mononucleotide, dihydronicotinamide mononucleotide) is the reduced form of NMN. Published in the FASEB Journal (2021), research demonstrates that NMNH is a substantially more potent NAD+ enhancer than NMN — boosting NAD+ levels up to 10-fold in cells and over 5-fold in liver tissue, compared to NMN's modest 2-fold increase.
Unlike NMN, which degrades rapidly to nicotinamide (NAM) and loses efficacy, NMNH follows a unique metabolic pathway (CD73→ENT→AK→NMNAT) that bypasses the NRK and NAMPT bottlenecks. This results in faster onset (15 minutes vs. 1 hour), longer duration (>20 hours vs. 1-4 hours in blood), and broader tissue coverage — including brain, muscle, and heart where NMN shows no significant effect.
Every batch is manufactured under strict GMP conditions and tested against international quality standards. Each shipment includes a full Certificate of Analysis (COA) covering NMNH purity, particle size distribution, dissolution profile, microbial limits, and heavy metals. Our facility is ISO 9001, ISO 22000, FDA-registered, and Halal certified.
Published research data showing NMNH's superior NAD+ enhancement across tissues.
| Parameter | NMN | NMNH |
|---|---|---|
| NAD+ Enhancement (Cells) | ~2x | up to 10x |
| Liver NAD+ (in vivo) | Moderate | >5x increase |
| Onset Time | ~1 hour | 15 minutes |
| Blood NAD+ Duration | 1-4 hours | >20 hours |
| Brain NAD+ Elevation | No effect | Significant |
| Muscle & Heart NAD+ | No effect | Significant |
| Metabolic Pathway | NRK/NAMPT-dependent | CD73/ENT/AK pathway |
| Degradation to NAM | Rapid | No |
The unique metabolic pathway and sustained-release technology that make NMNH superior.
NMNH is encapsulated in a multi-core soluble wall matrix, protecting it from degradation and enabling intestinal-targeted delivery.
NMNH follows the CD73→ENT→AK→NMNAT pathway, bypassing the NRK/NAMPT bottlenecks that limit NMN efficacy.
Crosses the blood-brain barrier and elevates NAD+ in brain, muscle, heart, and brown fat — tissues where NMN is ineffective.
24-hour sustained release maintains elevated NAD+ levels throughout the day, maximizing therapeutic benefit.
A four-layer engineered micro-pellet designed for maximum stability and targeted delivery.
Acid-resistant outer shell
Protects the pellet from gastric acid degradation. Dissolves only at pH 6.0+ in the intestine, ensuring NMNH survives stomach transit intact and reaches the absorption site.
24-hour controlled release
Semi-permeable polymer film that controls the release rate of NMNH. Regulates diffusion to maintain steady blood NAD+ levels for over 20 hours.
Multi-core encapsulation
Patented "multi-core + soluble wall" structure. Completely isolates NMNH from oxygen, moisture, and light. Dissolves fully in the intestine, releasing NMNH for the unique CD73 pathway.
≥98% purity reduced NMN
Nano-scale NMNH crystals encapsulated in multi-core format. The reduced form of NMN, 5x more potent than NMN, follows a unique metabolic pathway bypassing NRK/NAMPT bottlenecks.
How the four-layer pellet delivers NMNH through the unique CD73 pathway to elevate NAD+ across 6 tissues.
Pellet swallowed with water. Enteric coating seals NMNH inside, protected from oxygen, moisture, and stomach acid.
Gastric acid (pH 1.5-3.5) attacks the pellet. Enteric coating resists acid — NMNH stays 100% protected, no degradation to NAM.
At pH 6.0+, the coating dissolves. NMNH is released and enters the CD73→ENT→AK→NMNAT pathway, bypassing NRK/NAMPT bottlenecks.
NMNH absorbed into blood within 15 minutes. Uniquely crosses the blood-brain barrier — elevating NAD+ in brain, muscle, and heart where NMN fails.
NAD+ elevated across liver, kidney, brain, muscle, heart, brown fat — sustaining >20 hours. 10x more potent than NMN, activating Sirtuins and DNA repair.
Diverse applications across pharmaceutical, nutraceutical, and functional food industries.
Superior NAD+ replenishment activates Sirtuins and supports DNA repair. 5x more potent than NMN for reversing age-related NAD+ decline.
Directly fuels mitochondrial ATP production. Sustained NAD+ elevation supports all-day energy metabolism and combats fatigue.
Uniquely crosses the blood-brain barrier to elevate brain NAD+ — something NMN cannot achieve. Supports neuroprotection and memory.
Published research shows NMNH reduces KIM-1 injury markers, restores mitochondrial function, and accelerates tubular cell repair in AKI models.
Elevates NAD+ in skeletal muscle where NMN has no effect. Supports energy metabolism, endurance, and recovery in athletic applications.
Enhances NAD+ in brown fat and heart tissue. Supports metabolic regulation, cardiovascular health, and healthy weight management.
Peer-reviewed research validating NMNH's superiority over NMN.
In cell studies, NMNH boosts NAD+ up to 10-fold vs. NMN's 2-fold.
NMNH elevates NAD+ within 15 minutes, vs. 1 hour for NMN.
Blood NAD+ remains elevated for 20+ hours, vs. 1-4h for NMN.
Liver, kidney, brain, muscle, heart, brown fat — vs. only 2 for NMN.
Reference: Zapata-Pérez R, et al. "Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice." FASEB Journal, 2021, 35(4). DOI: 10.1096/fj.202001826R
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